Microbe Kombat is an action game developed by Hero Interactive. Released in 2008, it follows the action of being a microbe in a hostile environment. Generally, the game has received positive reviews for its quirkiness, entertainment, and fast-paced action. However, it has been criticized due to the fact that some of the enemy microbes are immune to viruses, which can kill your player in seconds if you're not careful. Overall, however, Microbe Kombat is a successful game.
You play the game with only your mouse, through moving your player microbe with the mouse cursor and clicking options and powerups with the mouse button.
Pixel - A similar game, in being fast paced and actiony.